Important.

BY GREGORY ZUCKERMAN
Bain Capital,Kohlberg Kravis Roberts & Co., Bank of America Corp. and the brother of former Senate Majority Leader William Frist are each in line to make nearly $3 billion from $1.2 billion investments in the 2006 leveraged buyout of hospital chain HCA Holdings Inc.

The gain—about 250% over five years that were trying for the economy and health-care companies—would amount to one of the largest ever from a private-equity deal.

The profits show the original attraction of $20 billion-plus "megadeals," which enjoyed a heyday during the credit boom last decade. Investing at such scale, with high leverage, can yield huge ...

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